Supplementary Data

Supplementary Data for the publication "Copy number losses of oncogenes and gains of tumor suppressor genes generate common driver mutations"This dataset includes:<b>Selection Estimates Across Copy Number States (S1)</b>: This section provides selection estimates for cancer genes, essential genes, and a set of random genes across different copy number states.<b>Selection Estimates in Diploid State (S2)</b>: Contains selection estimates for genes in their diploid state.<b>Conditional Selection Estimates for Gene Loss (S3)</b>: Contains conditional selection estimates for gene loss.<b>Conditional Selection Estimates for Gene Gain (S4)</b>: Contains conditional selection estimates for gene gain.<b>Cluster Identities for Cancer Gene-Tumor Type Pairs (S5)</b>: Provides the cluster identities for various cancer gene-tumor type pairs.<b>List of Cancer Types with the Largest Amount of Data in the Discovery Cohort (S6)</b>: Includes a comprehensive list of the largest cancer types in the discovery cohort.<br>本数据集为发表于《致癌基因（oncogene）拷贝数缺失与抑癌基因（tumor suppressor gene）拷贝数扩增产生常见驱动突变（driver mutation）》的补充数据。本数据集包含以下内容：<b>跨拷贝数（copy number）状态的选择估计值（S1）</b>：本章节提供了癌症基因、必需基因（essential genes）以及一组随机基因在不同拷贝数状态下的选择估计值。<b>二倍体状态（diploid state）下的选择估计值（S2）</b>：收录了基因处于二倍体状态时的选择估计值。<b>基因缺失（gene loss）的条件选择估计值（S3）</b>：收录了基因缺失场景下的条件选择估计值。<b>基因扩增（gene gain）的条件选择估计值（S4）</b>：收录了基因扩增场景下的条件选择估计值。<b>癌症基因-肿瘤类型配对的簇（cluster）标识（S5）</b>：提供了各类癌症基因与肿瘤类型配对的簇分类标识。<b>发现队列（discovery cohort）中数据量最大的癌症类型列表（S6）</b>：收录了发现队列中数据规模居前的各类癌症类型的完整列表。