We describe an approach, herein called single-cell protein and RNA co-profiling (SPARC), which enables measurement of global mRNA and high multiplex, targeted cellular proteins in single cells
Formation of the three primary germ layers during gastrulation is an essential step in the establishment of the vertebrate body plan. Recent studies employing single cell RNA-sequencing have identifie
Aging is defined as the functional decline of tissues and organisms, leading to many human conditions, such as cancer, neurodegenerative diseases, and hair loss. Although stem cell exhaustion is widel
