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Human embryonic stem cells contribute to embryonic and extraembryonic lineages in mouse embryos through inhibition of apoptosis

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NIAID Data Ecosystem2026-05-25 收录
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We generated hESCs with inducible expression of anti-apoptotic gene BCL2 and BCL2L1, and found that the BCL2- and BCL2L1-overexpression could inhibit apoptosis of hESCs without affecting their pluripotent state. Overall design: mRNA profiles of human embryonic stem cells with inducible expression of anti-apoptotic gene BCL2 and BCL2L1 were generated by RNA sequencing using Illumina HiSeq 4000

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2018-02-10
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