Immune prophylaxis and treatment of transplanted tissue rejection act indiscriminately, risking serious infections and malignancies. Although animal data suggest that cellular immune responses causing
Indications of PD-1/L1- and MAPK-targeted therapies cross cancer histologies. Rationally sequencing and/or combining them may overcome innate and acquired resistance. We observed increased clinical be
The clonal expansion of HIV-1-infected CD4+ T cells is a major barrier to cure. Using single-cell ECCITE-seq, we examined the transcriptional landscape, upstream immune regulators, HIV-1 RNA expressio
No refers to patient number in the Table 1; IFN-ON, CML patients with ongoing IFN-α therapy; IFN-OFF, CML patients who have discontinued the therapy; MPN myeloproliferative neoplasm.Clonality was dete
