cryo-EM structure of DkTx-bound minimal TRPV1 in open state

cryo-EM structure of DkTx-bound minimal TRPV1 in open state Descriptor: (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ... Authors: Zhang, K, Julius, D, Cheng, Y. Deposit date: 2020-12-17 Release date: 2021-09-22 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.47 Å) Cite: Structural snapshots of TRPV1 reveal mechanism of polymodal functionality. Cell, 184, 2021开放状态下结合DkTx的最小瞬时受体电位香草酸亚型1（Transient Receptor Potential Vanilloid 1, TRPV1）的冷冻电子显微镜（cryo-electron microscopy, cryo-EM）结构 描述物：(11R,14S)-17-氨基-14-羟基-8,14-二氧代-9,13,15-三氧杂-14λ⁵-磷杂十七烷-11-基癸酸酯、(2S)-1-(丁酰氧基)-3-{[(R)-羟基{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-五羟基环己基]氧基}磷酰基]氧基}丙-2-基十三烷酸酯、钠离子…… 作者：Zhang, K、Julius, D、Cheng, Y 提交日期：2020-12-17 发布日期：2021-09-22 最后修改日期：2024-11-20 方法：电子显微镜（3.47 Å） 引用文献：Structural snapshots of TRPV1 reveal mechanism of polymodal functionality. Cell, 184, 2021