Mutations in the X-linked CDKL5 gene cause CDKL5 deficiency disorder (CDD), a severe neurodevelopmental condition mainly characterized by infantile epileptic encephalopathy, intellectual disability, a
Intrauterine hypoxia is a common complication during pregnancy and could increase the risk of cardiovascular disease in offspring. However, the underlying mechanism is controversial. Memantine, an NMD
The fast diagnosis of the life-threatening acute radiation syndrome is crucial, as the early prediction of the hematological acute radiation syndrome (H-ARS) can save lives. Previously, we validated a
Pseudoxanthoma elasticum (PXE) is a genetic disease considered as a paradigm of ectopic mineralization disorders, being characterized by multisystem clinical manifestations due to progressive calcific
1P<0.05 for oneway ANOVA between MAT = 1, MAT≥ 100, and MAT≥400. 2P<0.05 for MAT = 0 vs MAT≥ 100. 3P<0.05 for MAT = 0 vs MAT≥ 400. 4P<0.05 for MAT≥ 100 vs MAT≥ 400. 5neutrophil gelatinase-associated l