Cultured cardiomyocytes treated with hyaluronan. Mus musculus

Investigation of the role of hyaluronan in cardiomyocytes . The aims of the study were to determine if cardiomyocytes are capable of detecting hyaluronan and if then intrecellular signaling causes changes in gene expression. The study showed that cardiomyocytes can bind hyaluronan with following change in gene expression. Overall design: Cultured cardiomyocytes were treated with hyaluronan in differrent length. Gene expression in cells were analyzed with Illumina Beadstation.