The activation induced cytosine deaminase (AID) mediates diversification of B cell immunoglobulin genes by the three distinct yet related processes of somatic hypermutation (SHM), class switch recombi

NIAID Data Ecosystem90

CLL stereotyped B-cell receptor immunoglobulin sequences are recurrent in the B-cell repertoire of healthy individuals: apparent lack of central and early peripheral tolerance censoring

B细胞受体

血液肿瘤免疫

CLL stereotyped B-cell receptor immunoglobulin sequences are recurrent in the B-cell repertoire of healthy individuals: apparent lack of central and early peripheral tolerance censoring

NIAID Data Ecosystem50

Comparative analysis of B-cell receptor repertoires induced by live yellow fever vaccine in young and middle age donors

免疫反应

B细胞受体

Immunoglobulin repertoires (top-1569 clonotypes) from healthy volunteers of two age groups, young and middle age. Plasma B cells were obtained from peripheral blood samples at 9th day after first vacc

DataCite Commons2020-08-28 更新90

Homo sapiens Raw sequence reads. Homo sapiens

B细胞受体

抗体发现研究

Includes BCR and antigen barcode libraries for:(1) Ramos B cell lines containing VRC01-expressing B cells and Fe53-expressing B cells(2) Donor NIAID45(3) NIAID donor N90

NIAID Data Ecosystem60

BCRseq of sorted human peripheral blood naive B cells

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