Cell survival was determined by MTT assay as described in Materials and Methods. aData in the table are shown as the means ± SD (n = 6) of at least three independent experiments. bRR value indicating
(Tab 1A-B) Plate configurations of the two Seahorse XFe96 plates used in the screen. Included are the MMV compounds that were injected into the indicated wells from Ports A-C during the first (Tab 1A)
As part of a larger effort to provide proof-of-concept in vitro only risk assessments, we have developed a suite of high throughput assays for key readouts in the p53 DNA damage response toxicity path