Global effects of spt10 mutations on gene expression in budding yeast.

Using yeast strains based on the protease-deficient strain BJ5459 (= wild type), the effects of the spt10-null and spt10-C388S mutations on global gene expression were assessed and compared本研究以蛋白酶缺陷菌株BJ5459（野生型，Wild Type）为基础构建的酵母菌株为实验材料，评估并比较了spt10基因敲除（spt10-null）突变与spt10-C388S突变对全基因组基因表达的影响。