HIV-1 burden influences host response to co-infection with Neisseria gonorrhoeae in vitro. Homo sapiens

Gene networks involved in HIV-1 infection of human PBMCs were investigated by dose dependant infection with HIV-1 (Bal). Perturbation of networks was evaluted using a co-infection with N. gonorrheae. Hierarchical clustering, fold change analysis, and contour mapping of genes was used to identify gene groups that were then anlayzed for statisically significant associations using EASE. Keywords: dose response