Accumulation of amyloid-beta (Aβ) into amyloid plaques and hyperphosphorylated tau into neurofibrillary tangles (NFTs) are pathological hallmarks of Alzheimer’s disease (AD). There is a significant in
ABSTRACT Background: Validation of cognitive instruments for detection of Alzheimer's disease (AD) based on correlation with diagnostic biomarkers allows more reliable identification of the disease.
Introduction: The goal of this study was to investigate and compare the classification performance of machine learning with behavioral data from standard neuropsychological tests, a cognitive task, or
Données issues de la cohorte MEMENTO, projet de recherche ayant pour objectifs de décrire et mieux comprendre l'évolution clinique de patients présentant des signes précoces pouvant évoquer la maladie
Note: NC, normal control; AD, Alzheimer's disease; MCInc, mild cognitive impairment patients who have not converted to AD within 24 months; MCIc, mild cognitive impairment patients who have converted