Direct Synthesis of N-Trifluoromethyl Amides via Photocatalytic Trifluoromethylamidation

Fig. 1. | Known methods for the synthesis of N-CF3 amides & our work design. Fig. 2. | Screening and synthesis of novel N-CF3 amidyl radical precursors. Fig. 3. | Trifluoromethylamination of (hetero)arenes Fig. 4. | Extended applications of radical trifluoromethylaminations. Fig. 5. | Radical aryltrifluoromethylaminations of alkenes/alkynes Fig. 6. | Plausible reaction mechanism & DFT studies.