首页/数据集/A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop

A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop

ChEBI2016-03-29 更新2026-07-12 收录

药物耐药机制

癌细胞重编程

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-79688 数据链接链接失效反馈

官方服务：

资源简介：

A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop

应用场景：

创建时间：

2016-03-29

癌细胞重编程

靶向药物研发

Table S1. Differentially expressed genes in high-PKM2 group. Table S2. Differentially expressed genes in low-PKM2 group. Table S3. Descriptive statistics of PKM2 and other clinical features grouped by

NIAID Data Ecosystem70

Y.T.,SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress of tumor cells

癌细胞重编程

癌症分子机制

Glutaminase regulates glutaminolysis for cancer cell proliferation. However, the mechanism underlying glutaminase activity regulation is largely unknown. Here we demonstrated that the kidney-type glut

NIAID Data Ecosystem20

Table_2_Knockout of ENO1 leads to metabolism reprogramming and tumor retardation in pancreatic cancer.docx

癌细胞重编程

癌靶点研究

The shift in glucose utilization from oxidative phosphorylation to glycolysis is the hallmark of tumor cells. The overexpression of ENO1, one of the key enzymes in the glycolysis process, has been ide

NIAID Data Ecosystem10

The SDHB Arg230His mutation causing familial paraganglioma alters glycolysis in a new Caenorhabditis elegans model

癌细胞重编程

线粒体功能障碍

The conserved B-subunit of succinate dehydrogenase (SDH) participates in the TCA cycle and mitochondrial electron transport. The Arg230His mutation in SDHB causes heritable pheochromocytoma/paragangl

NIAID Data Ecosystem30

Additional file 21 of Fine-tuning the metabolic rewiring and adaptation of translational machinery during an epithelial-mesenchymal transition in breast cancer cells

癌细胞重编程

基因表达调控

Additional file 21:. Supplementary File S1. Lists of genes with particular expression. Genes with high transcription and low translation comprise the group of red genes; genes with high transcription

Figshare2020-07-19 更新10

A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop

资源简介：

相关数据集