Diabetic Kidney Disease Induces Transcriptome Alterations Associated with Angiogenesis Activity in Human Mesenchymal Stromal Cells [mRNA]. Diabetic Kidney Disease Induces Transcriptome Alterations Associated with Angiogenesis Activity in Human Mesenchymal Stromal Cells [mRNA]

To explore the angiogenic activity of MSC in DKD, the transcriptome of adipose tissue-derived MSC obtained from DKD subjects was compared to age-matched controls without diabetes or kidney impairment. Next-generation RNA sequencing was performed on MSC to identify differentially expressed messenger RNA and microRNA involved in angiogenesis. Overall design: mRNA-seq data for MSC from DKD and control participants