T_helper_Cell__differentiation__. T_helper_Cell__differentiation__

Study was designed to compare the transcriptome of Th2 cells in presence or absence of 4m8c. Murine splenic naive T helper cells were activated in presence of anti-CD3e, anti-CD28 antibodies and IL4 and IL2 cytokines for 3 days. Cells were then transferred from activation plate to resting for 3 days. Cells were reactivated by anti-CD3e antibidy. Similar culture were maintained in presence of 15uM 4m8c. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/