Asymmetric β‑Boration of α,β-Unsaturated N‑Acyloxazolidinones by [2.2]Paracyclophane-Based Bifunctional Catalyst

An efficient copper-catalyzed asymmetric conjugate boration has been achieved by exploiting a new planar and central chiral bicyclic triazolium ligand. This protocol was highly efficient and gave a variety of chiral secondary alkylboronates in 97–99% ee. A preliminary mechanistic study supports the bifunctional nature of the catalyst.通过利用一种新型的平面且中心的手性双环三唑鎓配体，成功实现了高效的铜催化非对称共轭硼化反应。该方案具有较高的效率，在97-99%的ee值下，得到了多种手性二级烷基硼酸酯。初步的机理研究表明，该催化剂具有双官能团性质。