This is the reverse drug-induced gene expression log2 fold change profiles based on the Level 3 data of LINCS. Only the FDA-approved drugs were considered.
Original cell wound closure for Fig 2B. Original cell migration for Fig 2D. Original tube formation numbers for Fig 2F. Original microvessels number for Fig 3B. Original microvascular branches number
Aims: We propose a novel machine learning approach to expand the knowledge about drug-target interactions. Our method may help to develop effective, less harmful treatment strategies and to enable the
Datasets from a study in which network-based methodologies were used to identify potential repurposable drugs and drug combinations for successfully targeting the 2019 novel coronavirus.
