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Multicomponent Approach in the Synthesis of 2,2,6-Trisubstituted Morpholine Derivatives

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NIAID Data Ecosystem2026-03-09 收录
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An efficient synthesis of 2,2,6-trisubstituted morpholine is described which involves a multicomponent process by simply mixing epichlorohydrin, N-bromosuccinimide, nosyl amide, and an olefin. The products contain chloride handles which are suitable for further modification.

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2016-02-20
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