Ac4c modifications down-regulation in macrophages promotes suppressive tumor microenvironment in HCC

To investigated how NAT10 inhibitor (Remodelin hydrobromide) affected the function of peritoneal macrophages , we treated peritoneal macrophages IFN y,Remodelin hydrobromide and Remodelin hydrobromide with IFN y. We then performed gene expression profiling analysis using data obtained from RNA-seq of peritoneal macrophages with four treaments Overall design: Comparative gene expression profiling analysis of RNA-seq data for treated with IFNy,Remodelin hydrobromide and Remodelin hydrobromide with IFNy.