Treatment outcomes by WT-IRF8 expression.

OR = odds ratio; HR = hazard ratio; Events = relapses from CR or death from any cause; CI = confidence interval.P = two-sided p-value from logistic regression (CR, RD) or proportional hazards regression (OS, RFS), treating WT-IRF8 expression as a dichotomous variable (“Two groups”, i.e., >2-fold vs. ≤2-fold) or as a continuous variable (“Trend”).“Adjusted” analyses include the following covariates, which were identified as significant in multivariate analyses:CR: age, CD34 expression (fold-change), and performance status (2–3 vs. 0–1);RD: age, CD34 expression, and FLT3-ITD (present vs. absent);OS: age, CD34 expression, and performance status;RFS: age.