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Polygenic Risk Scores (PRSs) for cardiometabolic diseases used to identify associated plasma protein changes

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Figshare2019-12-14 更新2026-04-08 收录
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Polygenic risk scores (PRS) for:<br><br>- Atrial Fibrillation- Chronic Kidney Disease (CKD)<br>- Type 2 Diabetes (T2D)<br>- Stroke (any type)<br><br>These scores were used to test associations between polygenic risk of these diseases and levels of 3,442 plasma proteins in 3,175 healthy individuals from the INTERVAL blood donor cohort.<br><br>Each PRS file contains a set of 1.96 - 2.21 million SNPs, their genomic location (hg19/GRCh37 coordinates), and weights (effect sizes from GWAS).<br><br>

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2019-12-14
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