Sensitivity and specificity of CDO1 methylation in multple types of human cancer.

TaqMeth V is expressed as mean ± SD, and TaqMeth V is described in Materials and Methods. aP value was derived from Wilcoxon-Mann-Whitney test of aPT vs. PN; bPT vs. NN only in lung. PT, tumor tissue from cancer patients; PN, normal tissue from cancer patients; NN, normal tissue from non-cancer patients. AUROC is expressed as mean ± SD, and optimal cut-off values were calculated from ROC analysis. Methylation level below the cut-offs was considered as unmethylated and over the cut-offs were as methylated. cP value in ROC analysis; dP value in Fisher’s exact test. Sensitivity, positive methylation/total tumor cases; Specificity, negative methylation/total normal cases.