Gut microbiota is a constant source of antigens and stimuli to which the resident immune system has developed tolerance. However, the mechanisms by which mononuclear phagocytes, specifically monocytes

NIAID Data Ecosystem60

Additional file 9 of Epigenetic regulation of innate immune memory in microglia

表观遗传学

免疫记忆

Additional file 9: Annotated differential ATAC, H3K4me3 and H3K27ac peaks in microglia of PL versus PP, PL versus LL and LL versus LP mice (related to Fig. 3A, 3B, 3C).

DataCite Commons2024-02-20 更新40

Extracellular trap can be trained as a memory response

免疫记忆

中性粒细胞胞外陷阱

Extracellular trap (ET) appears as a double-edged sword for the host since it participates in host immune defense by entrapping pathogens, while excessive ET release also contributes to various diseas

DataCite Commons2024-03-21 更新70

Tim-3-Expressing CD4 + and CD8 + T Cells in Human Tuberculosis (TB) Exhibit Polarized Effector Memory Phenotypes and Stronger Anti-TB Effector Functions

牛结核病与副结核病免疫机制

T细胞效应功能

T-cell immune responses modulated by T-cell immunoglobulin and mucin domain-containing molecule 3 (Tim-3) during Mycobacterium tuberculosis (Mtb) infection in humans remain poorly understood. Here, we

NIAID Data Ecosystem40

CD4+ T-cell help creates effector memory CTLs with innate and help-independent recall capacities

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