BackgroundNAFLD (Nonalcoholic fatty liver disease) is becoming an increasingly common cause of chronic liver disease. Metabolic dysfunction, overweight/obesity, and diabetes are thought to be closely
Additional file 1: Table S1. Studies analyzed in this systematic review. Table S2. Summary of the biomarker candidates identified across different studies. Table S3. Functional-enrichment analysis of
Additional file 2: Table T2. List of differentially methylated regions between type 1 diabetes exposed offspring and controls. Displayed are regions with a crude p < 0.005.
Objective: Diabetes mellitus type 1 (T1D) incidence is increasing in pediatric population. Good metabolic control, measured by glycated hemoglobin (HbA1c), significantly reduces the risk for chronic c