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Chromatin architecture of B cell development during the humoral immune response. Chromatin architecture of B cell development during the humoral immune response

NIAID Data Ecosystem2026-03-12 收录

B细胞发育

染色质架构

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA762037 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2021-09-09

B细胞发育

免疫表型

* This is the current accepted phenotype for immature B cells. Because we used historic data for these analyses, we felt it appropriate to indicate in the text the criteria used in the actual labeling

NIAID Data Ecosystem40

YY1 stabilizes super enhancer-promoter loops and gene expression during mesenchymal stem cell aging (Hi-C)

干细胞衰老

染色质架构

Stem cell aging leads to a progressive functional decline in self-renewal and differentiation capacity. How chromatin architecture impacts the gene expression changes that underlie altered stem cell f

NIAID Data Ecosystem20

Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans.

免疫代谢

B细胞发育

Transcriptional profiling of transitional and follicular B cells showed that metabolic quiescence was acquired at the follicular B cell stage in both humans and mice, characterized by an orchestrated

NIAID Data Ecosystem10

B cell development requires discrete regulation by PTEN-PI3K and mTOR pathways and the intricate interplay with IL-7 r-Stat5 signaling

B细胞发育

免疫信号通路

IL-7 r and Stat5 signaling drives early B lymphopoiesis, but it remains poorly understood how Stat5-dependent and independent pathways contribute to this process. We report the discrete effects of PI3

NIAID Data Ecosystem30

Transcriptommic profiling of hematopoietic progenitor cells following PCGF1 loss [RNA-Seq]. Transcriptommic profiling of hematopoietic progenitor cells following PCGF1 loss [RNA-Seq]

造血干细胞

B细胞发育

Polycomb proteins are epigenetic regulators important for cell fate decision and maintenance. Here we show that PCGF1, one of components of Polycomb repressive complex (PRC) 1 is important for the dif

NIAID Data Ecosystem20

Chromatin architecture of B cell development during the humoral immune response. Chromatin architecture of B cell development during the humoral immune response

资源简介：

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