Identification of novel MeCP2 cancer-associated target genes
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Identification of novel MeCP2 cancer-associated target genes
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2020-10-02
相关数据集
Molecular pathogenesis of several neurodevelopmental disorders converges on MeCP2-TCF20 complex interactions
Neurodevelopmental disorders (NDDs) are genetically heterogeneous, yet often share certain features such as intellectual disability or motor incoordination. MeCP2 dysfunction is associated with MECP2
NIAID Data Ecosystem50
Identification of the methyl-CpG binding protein 2 (MeCP2) interacting proteins in the high molecular weight (HMW) extract prepared from the human HEK293T cells by immunoprecipitation coupled with mass spectrometry analysis
Identification of the methyl-CpG binding protein 2 (MeCP2) interacting proteins in the high molecular weight (HMW) extract prepared from the human HEK293T cells by immunoprecipitation coupled with mas
integrated proteome resources50
MeCP2 regulates genome-wide gene expression through recognition of H3K27me3 [NanoString]
MeCP2 plays a multifaceted role in gene expression regulation and chromatin organization. Interaction between MeCP2 and methylated DNA to regulate gene expression is well established. However, the wid
NIAID Data Ecosystem40
Genome Wide Distribution of Linker Histone H1.0 is Independent of MeCP2 II. Genome Wide Distribution of Linker Histone H1.0 is Independent of MeCP2 II
Previous studies suggested that MeCP2 binds to linker DNA and competes with linker histone H1 to regulate chromatin structure, but this hypothesis has never been tested in vivo. Here, we expressed Fla
NIAID Data Ecosystem50
Hypothalamic gene expression data from Mecp2-null and MECP2-transgenic mice
We compared gene expression changes in the hypothalamus of mice lacking MeCP2 (Mecp2-null) and mice overexpressing MeCP2 (MECP2-transgenic). Mutations in the gene encoding the transcriptional represso
NIAID Data Ecosystem50
