Identification of cis-regulatory elements affecting pancreatic Islet maturation using chromatin accessibility variations. Identification of cis-regulatory elements affecting pancreatic Islet maturation using chromatin accessibility variations

we were able to find several known and unforeseen key transcriptional regulators acting at cis-regulatory sites and promoters which depicted a differential accessibility and induced differential gene expression along maturation. Overall design: ATAC-seq of Post natal 10 days (P10) and adults rats (N=3)