Background: White adipose tissue (WAT) browning is a promising target for obesity prevention and treatment. Empagliflozin has emerged as an agent with weight-loss potential in clinical and in vivo stu

NIAID Data Ecosystem40

A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro

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JAK抑制剂靶点

The Janus kinases (Jaks) are hubs in the signaling process of more than 50 cytokine or hormone receptors. However, the function of Jak in bone metabolism remains to be elucidated. Here, we showed that

NIAID Data Ecosystem20

Gene expression profile in Liver, skeletal muscle, brown and white adipose tissues in mice after different interventions. Mus musculus

基因表达

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SIRT1 is a NAD+-dependent protein deacetylase. SIRT1 plays key roles in metabolic regulation and adaptation. In this study, we wanted to compare gene expression profile in SIRT1 overexpressing mice to

NIAID Data Ecosystem60

Data_Sheet_2_Comparison of Calcium Balancing Strategies During Hypothermic Acclimation of Tilapia (Oreochromis mossambicus) and Goldfish (Carassius auratus).PDF

鱼类低温适应

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The body temperatures of teleost species fluctuate following changes in the aquatic environment. As such, decreased water temperature lowers the rates of biochemical reactions and affects many physiol

NIAID Data Ecosystem30

Transcriptome data of Vibrio parahaemolyticus

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