Iron is both, an essential compound for many metabolic processes, and iron deficiency can impact on the proliferation of cells including lymphocytes but also tumor cells. On the other hand, excess iro
C ontext: Septic cardiomyopathy is a severe condition with limited effective therapeutics. Astragaloside IV (AS-IV) has been reported to exert antioxidant and anti-inflammatory activities
Given the need to improve the efficacy of standard-of-care immunotherapy (anti-CTLA-4 + anti-PD-1) in human malignant pleural mesothelioma (hMPM), we thoroughly characterized the immunobiology of the