Comparison of network metrics with longitudinal scans between male (n = 12) and female (n = 14).

The statistical results were computed with a two-way linear mixed model with longitudinal time as within-subject fact, gender as between-subject factor and time by gender as interaction. The effect of age at 1st scan, handedness, education level, and brain size were adjusted for all of these analyses. Post-hoc results of the global topological measures were detailed in Fig. 4. Bold indicates variables that are statistically significant (p < 0.05), italic indicates variables that show trend of significance (p < 0.10). Comparison of network metrics with longitudinal scans between male (n = 12) and female (n = 14).