Recapitulating early human development with 8C-like cells
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2022-09-14
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Gene expression profile at single cell level of haploid partenogenotes and androgenotes from pronuclear stage to four divisions. Gene expression profile at single cell level of haploid partenogenotes and androgenotes from pronuclear stage to four divisions
Partenogentoes and Androgenotes are constructs artificially conceived which are genetically composed of the unique genome corresponding to the original haploid germ cell used for their generation (ooc
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Widespread expression of MyoD genes in Xenopus embryos is amplified in presumptive muscle as a delayed response to mesoderm induction.
The MyoD gene codes for an important regulatory factor in skeletal myogenesis. To explore the relationship between mesoderm induction in Xenopus embryos and expression of MyoD, I have monitored MyoD m
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Lethal phenotype-based database screening identifies ceramide as a negative regulator of primitive streak formation. Lethal phenotype-based database screening identifies ceramide as a negative regulator of primitive streak formation
In early embryogenesis, the primitive streak (PrS) generates the mesendoderm and is essential for organogenesis. However, because the PrS is a minute and transient tissue, elucidating the mechanism of
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PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability
Piwi proteins are important for germ cell development and function in almost all animals studied thus far. These proteins are guided to specific targets, such as transposable elements, by small guide
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Antisense c-myc effects on preimplantation mouse embryo development.
Antisense DNA inhibition of gene expression was explored as an approach toward elucidating mechanisms regulating development of preimplantation mammalian embryos. Specifically, a role for the c-myc pr
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