Genome-wide association studies for myopia in related and unrelated individuals

A GWAS for myopia was performed in unrelated individuals from UK Biobank (n = 25,804 cases; n = 40,969 controls) conducted using PLINK v2.A GWAS for myopia was performed in related individuals from UK Biobank (n = 35,531 cases; n = 57,505 controls) conducted using SAIGE/GATE.FILE INDEX:SNP = Variant identifierCHR = Chromosome on genome build GRCh37POS = Position on genome build GRCh37EFFECT_ALLELE = Effect alleleNON_EFFECT_ALLELE = Non-effect alleleOR = Odds ratio of outcome per copy of the risk alleleBETA = Effect size (log(OR) scale) of outcome per copy of the risk alleleSE = Standard error of effect sizeP = P-value of effect