These data are the primary data of the paper "A High-Fat Diet Reverses Metabolic Disorders and Premature Aging by Modulating Insulin and IGF1 Signaling in SIRT6 Knockout Mice"

NIAID Data Ecosystem10

Kidney RNA expression levels in the Hybrid Rat Diversity Panel for the PhenoGen website (https://phenogen.org)

器官转录组学

系统遗传学

As part of the PhenoGen Project (https://phenogen.org), kidney RNA-Seq data has been collected from the HXB/BXH recombinant inbred rat panel, which is part of the Hybrid Rat Diversity Panel (HRDP). RN

NIAID Data Ecosystem00

Embryonic allele distribution in the VCL-ΔIn20/21 mouse line.

基因敲除小鼠

胚胎发育研究

Genotype distribution was determined at different developmental stages. Homozygous VCL-ΔIn20/21 embryos were detectable until embryonal day E12.5. No homozygous animals were born.

NIAID Data Ecosystem20

Hepatic gene expression of WT and RHBDL4/RHBDD1 knockout mice fed normal chow or Western diet

基因敲除小鼠

代谢物转录组学

The rhomboid protease RHBDL4 cleaves SREBP-1. To understand the role of RHBDL4 in the liver, we generated RHBDL4 knockout (KO) mice using the CRISPR/Cas9 system and confirmed that cleaved SREBP-1 was

NIAID Data Ecosystem00

RNA-Seq data of PTCs-specific Insig1-knockout mice

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