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The chromatin accessibility landscape reveals distinct transcriptional regulation in the induction of human primordial germ cell-like cells from pluripotent stem cells

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NIAID Data Ecosystem2026-03-12 收录
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The accessibility chromatin patterns during hPGCLCs undergo a diverse changes in absence of SOX15. The consequence of these changes lead to a somatic gene network activation that leads to decrease hPGCLC at late stage Overall design: We analyzed the acessible genome profiles in human primordial germ cell like cells (hPGCLCs) comparing to SOX15-/-

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2021-05-06
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