Transcription dosage compensation does not occur in Down syndrome
收藏NIAID Data Ecosystem2026-05-01 收录
官方服务：
资源简介：
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
应用场景：
创建时间：
2023-12-06
相关数据集
Additional file 9 of Dosage compensation of Z sex chromosome genes in avian fibroblast cells
Additional file 9: Table S8. Effect of medium on RPS6 expression. Differential expression analysis for DMEM/10�S vs DMEM/F12/10�S
Figshare2024-08-16 更新100
RNA-on-X 1 and 2 in Drosophila melanogaster fulfill separate functions in dosage compensation
In Drosophila melanogaster, the male-specific lethal (MSL) complex plays a key role in dosage compensation by stimulating expression of male X-chromosome genes. It consists of MSL proteins and two lon
NIAID Data Ecosystem50
Condensin IDC, H4K20me1, and perinuclear tethering maintain X chromosome repression in C. elegans. Condensin IDC, H4K20me1, and perinuclear tethering maintain X chromosome repression in C. elegans
Dosage compensation in Caenorhabditis elegans equalizes X-linked gene expression between XX hermaphrodites and XO males. The process depends on a condensin-containing dosage compensation complex (DCC)
NIAID Data Ecosystem20
Expression analysis in mouse female PGK12.1 ES cells by RNA-seq
Many animal species employ a chromosome-based mechanism of sex determination, which has led to coordinate evolution of dosage compensation systems. Dosage compensation not only corrects the imbalance
NIAID Data Ecosystem70
Binding of an X-specific condensin correlates with a reduction in active histone modifications at gene regulatory elements. Binding of an X-specific condensin correlates with a reduction in active histone modifications at gene regulatory elements
Condensins are evolutionarily conserved protein complexes that are required for chromosome segregation during cell division and genome organization during interphase. In C. elegans, a specialized cond
NIAID Data Ecosystem40
