Comparison between neonatal and adult heart valve and vascular tissue Tissue engineering of blood vessels and heart valves aims to create high quality prostheses, with preservation of their growth pot
Cardiovascular tissue engineering is a promising approach to develop grafts that, in contrast to current replacement grafts, have the capacity to grow and remodel like native tissues. This approach la
Purpose: To explore detailed transcriptome changes during the transition from fibroblasts toward cardiac cells Methods: We performed single-cell RNA-seq on MTTFs (11,580 cells) and MTTFs treated with
Coronary artery disease is among the primary causes of death worldwide. While synthetic grafts allow replacement of diseased tissue, mismatched mechanical properties between graft and native tissue re