Targeted gRNA screen against putative nucleic-acid binding proteins in a differentiation reporter strain context. By looking for gRNAs enriched in parasites no longer able to activate reporter express
We designed CRISPR-Cas9 whole genome screens to identify and rank critical genes for cholesterol metabolism in modified LDL treated BMDMs Overall design: Identify and rank critical genes for cholester
Cell-permeable peptides (CPPs) allow intracellular delivery of cargo molecules that are hooked to them. CPPs provide an efficient methodology to transfer bioactive molecules in cells, in particular in
Annexin A1 (ANXA1) is a Ca2+-binding protein involved in pancreatic cancer (PC) progression. It is able to mediate cytoskeletal organization maintaining a malignant phenotype. ANXA1 Knock-Out (KO) MIA
