TDP-43 dysfunction restricts dendritic complexity by inhibiting CREB activation and altering gene expression. TDP-43 dysfunction restricts dendritic complexity by inhibiting CREB activation and altering gene expression
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Identified TDP-43 targets in rat cortical neurons, many related to the CREB pathway Overall design: First application of TRIBE in mammalian system, used human ADAR2 catalytic domain for the experiment. Expression of TRIBE construct via lentiviral trasduction in rat cortical neurons
创建时间：
2020-03-23
