IMPRINTS-CETSA Docetaxel and Paclitaxel in MCF-7 cells, 8h incubation

NIAID Data Ecosystem2026-05-02 收录

药物靶点发现

化疗疗效评估

数据链接：

https://www.omicsdi.org/dataset/pride/PXD056176 数据链接链接失效反馈

官方服务：

资源简介：

IMPRINTS-CETSA data acquisition of MCF-7 cells treated with Vehicle (DMSO), Docetaxel or Paclitaxel using TMT 10 plex.

创建时间：

2024-10-23

Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders

药物靶点发现

神经药理学

A series of potent and selective [1,2,4]triazolo[1,5-a]pyrimidine PDE2a inhibitors is reported. The design and improvement of the binding properties of this series was achieved using X-ray crystal

NIAID Data Ecosystem110

The 1-therapeutic bullets of the case study from Therapeutic target discovery using Boolean network attractors: improvements of kali

药物靶点发现

布尔网络分析

All the therapeutic bullets made of 1 target returned by kali on the case study.

Figshare2018-01-27 更新10

Univariate Cox regression analysis of 4-year progression-free survival and overall survival in relation to patients’ characteristics.

癌症生存分析

化疗疗效评估

a. only oral regimens: XELODA and UFUR groups;b. combined regimens: FOLFOX, XELOX, OXA then 5-FU and FL groups.Abbreviations: 4-y OS: 4-year overall survival; 4-y PFS: 4-year progression-free survival

Figshare2015-12-03 更新00

Crystal structure of the first bromodomain of human BRD4 in complex with SJ001010551-2

蛋白质晶体学

药物靶点发现

Crystal structure of the first bromodomain of human BRD4 in complex with SJ001010551-2 Descriptor: 1,2-ETHANEDIOL, 2-[(6S,10S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a]

Protein Data Bank Japan2023-10-18 更新50

Crystal structure of Mutant N87T of adenosine/Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with Adenine

寄生虫酶结构

药物靶点发现

Crystal structure of Mutant N87T of adenosine/Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with Adenine

NIAID Data Ecosystem00