Background and Aims: Recent identification of intracellular DNA sensing pathways and involvement in numerous diverse disease processes including viral pathogenesis and autoimmunity suggests a role for
Analysis of the effect of BCR/CD40/IFN-γ/IL21 on human B cells at gene expression level. Overall design: Total RNA samples were obtained from human memory B cells subjected to 24 hours of in vitro cul
Patients afflicted with STING gain-of-function mutations frequently present with debilitating interstitial lung disease (ILD) that is recapitulated in mice expressing the STINGV154M mutation (VM). Pri
