Skeletal muscle satellite cells (SCs) are muscle stem cells responsible for muscle development and injury induced muscle regeneration. The pace of SC related study, however, is constrained partially b

NIAID Data Ecosystem20

Concurrent progress of reprogramming and gene-correction to overcome limitation of gene therapy of ALK2 mutant iPSCs

干细胞基因编辑

遗传病疾病建模

To ameliorate the cumbersome processes of reprogramming and subsequent gene-editing in vulnerable iPSCs, we have developed a greatly simplified one-step procedure, simultaneously introducing reprogram

NIAID Data Ecosystem30

EXOMEseq_of_HIPSCI_clones

干细胞基因编辑

外显子测序

After genetic modification of the KOLF2C1 human Induced Pluripotent Stem cell, we are confirming the absence of additional somatic variants by performing Exome sequencing. KOLF3 IPSC subclones are al

NIAID Data Ecosystem30

Gene targeting of the <i>NANOG</i> locus in hESCs.

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