There is limited understanding of how immune-mediated damage impacts intestinal stem cells (ISCs). We found that stem cell compartment injury is a shared feature of both alloreactive and autoreactive
To characterize transcriptional changes associated with gain of the transcription factor PLAG1-S that could contribute to transient ex vivo expansion of human cord-blood (CB) derived HSC we performed
Background: The High temperature requirement A 1 (HtrA1) is a multidomain secretory protein with serine-protease activity involved in the regulation of many cellular processes in both physiological an