Microglia, the resident immune cells of the central nervous system (CNS), are responsible for maintaining homeostasis in the brain by clearing debris and are suggested to be inefficient in Alzheimer’s
We examined the role of TREM2 on microglia responses to demyelination Overall design: Microglia were FACS-purified from WT or Trem2-/- mice fed with 0.2% cuprizone diet.
Title: Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice Tables providing cell-type specific gene expression differences and WGCNA analyses
