The extraction of metabolites from the Panchagavya was carried out using two methods: multi-solvent and aqueous. In the multi-solvent method, methanol, acetonitrile, and water were used in the ratios
%RSE: relative standard error (%RSE = 100 x standard error/parameter estimate), CI: confidence interval, kel: elimination rate, Tlag: lag time to elimination, Tlag_add_rit: additional lag time to elim
IVM or MOX was administered to Mdr1ab(−/−) mice (6 per dose rate) or to wild-type mice (3 per dose rate) at increasing doses below the LD50 to ensure a non-lethal effect of the administration. Drug co
We present data on the novel LC-MS/MS method for the determination of unbound tacrolimus. The method was developed experimentally and fully validated. We present the results of LC-MS/MS mesurements in
