SARS-CoV-2 Mpro in complex with compound 3

SARS-CoV-2 Mpro in complex with compound 3 Descriptor: 3C-like proteinase nsp5, N-[(2S)-3-cyclopropyl-1-{[(2R)-1-hydroxy-4-(methanesulfonyl)butan-2-yl]amino}-1-oxopropan-2-yl]-4-methoxy-1H-indole-2-carboxamide Authors: Bigelow, L, Tang, H, Boguslaw, N, Duda, D.M. Deposit date: 2024-10-02 Release date: 2025-04-30 Last modified: 2025-08-06 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Inhibition of dimeric SARS-CoV-2 Mpro displays positive cooperativity and a mixture of covalent and non-covalent binding. Iscience, 28, 2025