*Adult = 15 years or older, child = less than 15 years old.S = streptomycin; R = rifampcin; H = isoniazid; Z = pyrazinamide; T = thiacetazone; E = ethambutol. Large numbers indicate duration in months
Effective vaccines are urgently needed for the control of tuberculosis (TB). Here, we report that a mRNA TB vaccine is highly effective and exhibits both prophylactic and therapeutic activities in the