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CRISPR-Cas9 RAG2 Correction Simulation via Coding Sequence Replacement to Preserve Gene Regulation and Locus Structure

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NIAID Data Ecosystem2026-05-01 收录
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We present a method to correct the RAG2 gene while maintaining RAG2 expression regulation and locus structure and a workflow to determine the optimal configuration for CRISPR-Cas9 and rAAV6 correction of genes with strict spatiotemporal gene regulation.

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2023-09-23
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