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Galectin-3C in complex with dithiogalactoside derivative

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Galectin-3C in complex with dithiogalactoside derivative Descriptor: 5,6-bis(fluoranyl)-3-[[(2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,5-bis(oxidanyl)-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxan-2-yl]sulfanyl-3,5-bis(oxidanyl)oxan-4-yl]oxymethyl]chromen-2-one, Galectin-3 Authors: Kumar, R, Peterson, K, Nilsson, U.J, Logan, D.T. Deposit date: 2017-07-07 Release date: 2018-05-23 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.149 Å) Cite: Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity. J. Med. Chem., 61, 2018

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2017-07-07
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