This Test Guideline describes an in vivo erythrocyte Pig-a gene mutation assay (hereafter called the Pig-a assay) which uses an endogenous mammalian gene, the phosphatidylinositol glycan class A gene
Organisation for Economic Co-operation and Development150
This study aimed to explore the production of red pigment from Monascus purpureus in waste culture medium and its potential health benefits. Subsequently, the M. purpureus cultivated in a medium conta
Intake assessment and hazard profile of chemical substances are the two critical inputs in a safety assessment. Human intake assessment presents challenges that stem either from the absence of data or
Additional file 2: Supplementary Table 1. The gpt mutation frequencies in the testis of the AA or ENU-treated mice. Supplementary Table 2. The gpt mutation frequencies in the sperm of the AA or ENU-tr
Figure S7. Comparison of the negative and positive control counts for each strain with or without S9 mix. The doses shown in Figs. 6, 7, 8, 9, and 10 were used for comparison. The R2 values indicate t